Flexible Isolators
In our manufacturing facility, classified as ISO 7/8, we produce, in accordance with GMP requirements and clients’ specific needs, continuous liners and flexible isolators, sometimes called glove bags, to confine all the exposed operations or temporarily modified the inner atmosphere (cleaner area, low humidity or inert needs).
Similar to plastic bubbles with gloves, filters, zippered doors, wires and hoses pass through and any required tools, they are usually ad hoc products. They are made of basic pharma low-density polyethylene or Polyurethene films directly supplied by CSV Containment, but we can also transform material provided by third parties indicated by the end customers.
The always-increasing quality of our work and the effort to improve constantly have led several costumers to authorize us as Qualified flexible technology supplier.
ECP: from toxicology to a Containment Strategy
A proper containment strategy can be implemented, starting with a toxicology profile assessment performed by professionals in a pharmaceutical facility. OEL values (Occupational exposure limits derived from toxicological data) are used by pharmaceutical industries as a starting point to determine the containment strategy to apply, in the case of both a new facility and an […]
Pneumatic powder transfer from drums: a GMP dust-free solution!
Watch the video! A flexible system to confine pneumatic powder transfer operations, not only because of the material of the isolator but also because of the flexibility in serving drums of different diameters. Frequently, pneumatic systems operating in vacuum are used for pneumatic powder transfer operations, mainly to avoid handling drums and containers at height […]
SMEPAC Monitoring.
Containment and capability: two words that tell the story of CSV Containment’s world, but they also summarize the meaning of SMEPAC monitoring, aimed at verifying the safety of operators and equipment. Indeed, SMEPAC monitoring (Standardized Measurement of Equipment Particulate Airborne Concentration) is aimed at measuring the particulate containment performance of isolation systems used in the pharmaceutical […]
Contamination Reduction Device.
To reduce operators’ impact in Grade A areas, CSV Containment has developed a wearable, single-use, contamination reduction device, derived from our experience in the field of flexible isolators. New Annex 1 also concerns the containment of contamination risks. One of the new guidelines in particular requires that unsealed containers must be maintained in Grade A […]
Tray and Freeze Dryer Containment.
Tray and freeze dryer Containment via flexible isolators is the CSV solution when there are no alternatives to ensure operators and production safety. The tray and freeze dryer Containment is an example of how our flexible isolators can adapt to innovative and unusual situations and solve otherwise unmanageable problems. Bringing existing equipment to a containment […]
DIT® Flexible Isolators.
DIT® Flexible Isolators’ technology represents one of the most versatile solutions on the market for safe reactor charging. DIT® flexible isolators are the result of combining two experiences in which CSV Containment is achieving important results: materials processed in the “Flexilab” and patented iris technology. The materials, which are certified and produced in compliance with […]
Rotating dryer drum charging and discharging.
Drum charging and discharging in a rotating dryer have always been critical issues. However, CSV Containment doesn’t stop at much of anything! There are several problems concerning drum charging and discharging operations in a rotating dryer, first of all because of the need to contain coupling and decoupling at any charging step. In the second place, […]
Realizing custom flexible isolators in a short time: this is our mission!
A success story: the realization of Containment Flexible Isolators for an R&D department dedicated to the Pharmaceutical Technology of Oral Solid Products. CSV Containment isolators are proving to be more and more flexible, not only in terms of material but also in terms of how, where, and when they are used. The “how” is experienced […]